Bulldog Health
Bulldog Breeds
Evaluation of clomipramine as an adjunct to behavioural therapy in the treatment of separation-related problems in dogs
Forty-nine dogs showing signs of separation-related problems were randomly assigned to one of three groups: group A (15 dogs) received a placebo twice daily; group B (17 dogs) received clomipramine at 0.5 to 1.0 mg/kg twice daily; and group C (17 dogs) received clomipramine at 1.0 to 2.0 mg/kg twice daily. All the dogs also received behavioural therapy. Their owners were required to complete questionnaires about their dog's behaviour initially, and one, four and eight weeks after the treatment with clomipramine began. Bipolar ratings scales were used to monitor the frequencies of 'general', 'attachment-related' and 'separation-related' behaviours. Kruskal-Wallis tests and Kendall Rank correlations were used to determine any initial differences between the treatment groups, and the association between the initial scores and behavioural changes after one week of treatment with clomipramine. Extended Mantel-Haenszel statistics were used to evaluate the effects of clomipramine treatment versus the placebo, and Page's test was used to assess the effectiveness of behavioural therapy on its own. There were no significant differences in the demographic characteristics of the owners of the dogs assigned to the three groups. The dogs differed slightly in age between groups, and the dogs in the two clomipramine-treated groups were reported as showing problems at a significantly earlier age than those in the placebo group. Clomipramine treatment had a sustained suppressive effect on the dogs' general activity levels, and a more modest suppressive effect on their attachment-related tendency to want much physical contact with their owners. The typical signs of separation-related behaviour problems were not significantly affected by treatment with clomipramine, but behavioural therapy on its own was highly effective in reducing behavioural problems.
Department of Clinical Veterinary Medicine, University of Cambridge.
Podberscek AL, Hsu Y, Serpell JA.The Original Bulldog Club ->> The Bulldog Club of Milan ->>To promote and encourage the Breeding of Pure Bulldogs in all of the World, but more especially In the provinces of England, to Ireland, and in Scotland, in Italy, in Lombardy and in Milan.
Honorary President, Ever and Forever, Mrs. D.N. and Mr. Les Thorpe. Bulldog Club, creato per celebrare la incredibile nascita proprio a Milano, per merito esclusivo di Tuffnuts Bulldogs, in collaborazione con il The Bulldog International Research Center e con Ocobo Show Bulldogs, di quelli che, secondo i più profondi studi mondialmente dimostrabili, risulterebbero essere i più diretti discendenti e, quindi, i legittimi eredi di Rosa, il capostipite della Razza Bulldog, con genealogia integralmente inglese, Lincolnshire, Tuffnuts Ocobo. Il Club si è formato, infatti, nel Dicembre 2004 alla nascita di Tuffnuts Snow Angel Tuffnuts, dedicata al Maggiore L.A. Jackson ed a Dr. Les Cotton, il secondo Original Pure Breed Bulldog, nato a Milano ed in Italia dopo Tully, nato nel 2000, sempre nell ' Allevamento Tuffnuts Snow Angel. Per supportare la razza e tutti coloro che possiedono un Bulldog Inglese. Cucciolate disponibli, affidamento bulldogs, problemi di salute, riproduttori disponibili, etc..Il primo Club che si pone l'obiettivo di selezionare ed allevare anche il Bulldog Originale di Razza Pura, come era fino all' inizio del 20° secolo, con una genealogia completamente inglese, discendente dai più famosi Campioni della Storia.
